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ea0026p226 | Pituitary | ECE2011

Tumor occurrence or recurrence after five year GH replacement theraphy

Savanelli M C , Scarano E , Brunelli V , Lombardi G , Colao A , Di Somma C

GH replacement is widely used in adults with hypopituitarism, but its effect on tumor occurrence and pituitary tumor recurrence is unknown. Furthermore, in literature there are scant with short follow-up time. The available data do not seem to suggest that rhGH replacement increased the incidence of regrowth of pituitary tumor and of cancer in adults with GHD, provided that IGF1 concentrations remain within the normal range for age.The aim of our study w...

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ea0026p270 | Pituitary | ECE2011

Primary empty sella is associated with increased cardiovascular risk, regardless the occurrence of pituitary dysfunction

Torre M L , Cotta O R , Ferrau F , Di Mauro E , Albani A , Boschetti M , Teti C , Savanelli M C , Di Somma C , Alibrandi A , Ferone D , Cannavo S , Colao A

Introduction: Primary empty sella (PES) is a frequent incidental finding reported in 525% of general population and is associated with endocrine abnormalities in 860% of cases. In this collaborative multicentric study we evaluated cardiovascular risk by assessing clinical characteristics, glucidic profile and lipid parameters.Design: A total of 94 PES patients (39M-55F; mean age 50.3±0.9 years; mean BMI 28.9±0.5 kg/m<sup...

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Endocrine Abstracts

Tumor occurrence or recurrence after five year GH replacement theraphy

Primary empty sella is associated with increased cardiovascular risk, regardless the occurrence of pituitary dysfunction

BiosciAbstracts